Post COVID-19 side effects: Heart Damage! New reports suggest that Covid patients might have long-term cardiovascular effects. 78% of Covid-19 patients show heart complications after regaining health. The Boston Red Sox pitcher, Eduardo Rodriguez, confirmes that he is presently suffering from myocarditis linked to a recent COVID-19 diagnosis.
COVID- 19 continues to create significant morbidity and mortality worldwide. Thus far, the main prominence of the researchers conducted by the experts aims to determine respiratory complications, especially in critically ill patients. Further, a number of reports and small series suggested that Covid-19 notably affects the cardiovascular system by aggravating heart failure in patients with pre-existing cardiac illnesses and troponin boost in critically ill patients.
Therefore, the analysis might point down to one factor that is cardiac involvement and myocardial inflammation are common in recovered Covid-19 patients, as per the details issued by JAMA Cardiology.
Who were tested?
The scientist reviewed cardiac imaging outcomes of an unselected group of 100 patients who recently recovered from Covid-19. Where 53% of the patients were males and were in their late 40s.
Furthermore, treatment with hydroxychloroquine was initiated in a single patient but discontinued within days due to severe complications. Which basically suggest that hydroxychloroquine continues to be insignificant in the fight against Covid-19.Despite, several leaders including Donald Trump suggesting that hydroxychloroquine was effective against the virus.
The scientist traced patients who had experienced a wide variation of outcomes after their diagnosis. Interestingly only two out of the 100 patients were hooked on to ventilators.
What were the results?
All the patients who took part were subjected to cardiac MR imaging using “consistent and unified” procedures on 3T MRI scanners. The group was compared with 50 healthy control patients and 57 patients who had severe health complications.
The cardiac MR imaging concluded that a total of 78 patients who recovered from Covid-19 had unusual findings noticed by the standardized CMR.
The findings revealed an increase in myocardial native T1(73 patients), also an increase in myocardial native T2(60 patients), myocardial late gadolinium enhancement (32 patients) and pericardial enhancement (22 patients).
In this case native T1 and T2 mapping refer to promising techniques for quantitative assessment of diffuse myocardial pathologies. Also myocardial is also known as a heart attack in simple terms. Interestingly, native T1 imaging can detect myocardial abnormalities to a greater extent than T2 imaging.
Further, late gadolinium enhancement is basically a diagnostic tool for determining ischemic heart diseases. On the other hand, pericardial enhancement is a result of inflammation of the pericardium in reaction to illness or injury. It also can occur due to viral, bacterial, fungal or parasitic infections.
“The results of our study provide important insights into the prevalence of cardiovascular involvement in the early convalescent stage,” penned the lead author Valentina O. Puntmann, of the University Hospital Frankfurt in Germany, and colleagues. “Our findings demonstrate that participants with a relative paucity of preexisting cardiovascular condition and with mostly home-based recovery had frequent cardiac inflammatory involvement, which was similar to the hospitalized subgroup with regards to severity and extent. Our observations are concordant with early case reports in hospitalized patients showing a frequent presence of late gadolinium enhancement, diffuse inflammatory involvement, and significant rise of troponin T levels.”
Also, a boosted troponin T and C-reactive protein levels correspondingly show inflammatory and partially ongoing myocardial damage and have been correlated to worsen outcome, even if only marginally increased.
Furthermore, the group of analysts claimed that cardiac contribution appears to occur independently of the significance of the original Covid-19 infection. Also suggested that research with a much larger group was necessary to gather accurate information.
Therefore, looking at the information from the research conducted illustrates cardiac contribution in 78 patients and ongoing myocardial inflammation in 60 patients with recent Covid-19 illness, independent of pre-existing illnesses, harshness and overall course of acute illness, and the time from the original diagnosis.
Thereby, demonstrating that the ongoing studies points down to long-term cardiovascular effects of Covid-19.